A research team presented data indicating that Irreversible Pepsin Fraction (IPF) — a natural auto-antibody based fractionated protein — displays significant antiviral activity without indications of resistance.
The research was presented at the Fifth European Conference on Clinical and Social Research on AIDS and Drugs in Vilnius, Lithuania.
“We believe that IPF shows strong promise for a therapy that will stop or at least reduce the frequency with which HIV can enter a protected cell,”
IPF displayed spontaneous binding with glycoprotein 41, believed to be the “trap door” entrance for HIV into immune system cells. The study also indicates that IPF exhibits fusion inhibition of HIV with CD4 cells and increased gp41 and gp120 antigenic activity.
“The basic research indicates that it can lock the trap door known to be gp41. We hope to soon announce a trial in humans where we hope to confirm these findings.”
Source: HIV Plus Magazine | Compound Shows Anti-HIV Activity